Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
ROCK inhibitor |
| gptkbp:CASNumber |
146986-50-7
|
| gptkbp:effect |
modulates cell adhesion
inhibits smooth muscle contraction reduces cell migration |
| gptkbp:hasMolecularFormula |
C14H21N3O
|
| https://www.w3.org/2000/01/rdf-schema#label |
Y-27632
|
| gptkbp:inhibitedBy |
Rho-associated protein kinase (ROCK)
|
| gptkbp:isSolubleIn |
gptkb:DMSO
gptkb:water |
| gptkbp:IUPACName |
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide dihydrochloride
|
| gptkbp:meltingPoint |
>200°C
|
| gptkbp:PubChem_CID |
448045
CHEMBL25406 |
| gptkbp:used_in |
promote survival of dissociated human embryonic stem cells
reduce apoptosis in cell culture study cytoskeletal dynamics |
| gptkbp:used_in_research_for |
cell culture
neuroprotection stem cell survival |
| gptkbp:bfsParent |
gptkb:ROCK_(Rho-associated_kinase)
|
| gptkbp:bfsLayer |
7
|