Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
isoquinoline sulfonamide |
| gptkbp:approvedBy |
gptkb:Japan
|
| gptkbp:ATCCode |
C04AX28
|
| gptkbp:CASNumber |
103745-39-7
|
| gptkbp:chemicalFormula |
C14H17N3O2S
|
| gptkbp:compatibleWith |
gptkb:United_States
|
| gptkbp:developedBy |
gptkb:Japan
|
| gptkbp:discoveredBy |
gptkb:Asahi_Kasei
|
| gptkbp:hasSMILES |
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=CN=CC=C32
|
| gptkbp:hasUNII |
8X7Q0I84HV
|
| https://www.w3.org/2000/01/rdf-schema#label |
fasudil
|
| gptkbp:IUPACName |
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
|
| gptkbp:mechanismOfAction |
Rho kinase inhibitor
|
| gptkbp:molecularWeight |
291.37 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL1423
60714 D01536 DB04707 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
headache hypotension liver enzyme elevation |
| gptkbp:synonym |
Fasudil hydrochloride
HA-1077 |
| gptkbp:target |
Rho-associated protein kinase (ROCK)
|
| gptkbp:usedFor |
treatment of cerebral vasospasm
treatment of pulmonary hypertension |
| gptkbp:bfsParent |
gptkb:ROCK_(Rho-associated_kinase)
|
| gptkbp:bfsLayer |
7
|