RAC (Ras-related C3 botulinum toxin substrate)

URI: https://gptkb.org/entity/RAC_(Ras-related_C3_botulinum_toxin_substrate)
GPTKB entity
Statements (48)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:Rac1
gptkb:Rac
gptkbp:associatedWith gptkb:cancer
neurodevelopmental disorders
mental retardation
gptkbp:biologicalProcess GTPase activity
gptkbp:cellularComponent gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:encodedBy gptkb:RAC1_gene
gptkbp:function cell cycle progression
cell growth
cell migration
gene expression regulation
regulation of actin cytoskeleton
gptkbp:gene gptkb:RAC1
https://www.w3.org/2000/01/rdf-schema#label RAC (Ras-related C3 botulinum toxin substrate)
gptkbp:inhibitedBy gptkb:C3_exoenzyme
gptkbp:interactsWith gptkb:PAK1
gptkb:IQGAP1
gptkb:NADPH_oxidase_complex
gptkbp:length 192 amino acids
gptkbp:locatedOnChromosome gptkb:7p22
gptkbp:memberOf gptkb:Rho_family_of_GTPases
gptkbp:molecularWeight 21 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
gptkbp:PDB gptkb:1MH1
gptkbp:postTranslationalModification prenylation
phosphorylation
ubiquitination
gptkbp:regulates cellular senescence
neurite outgrowth
phagocytosis
cell polarity
cell adhesion
endocytosis
immune cell function
axon guidance
lamellipodia formation
reactive oxygen species production
gptkbp:structure gptkb:GTP-binding_domain
gptkbp:subcellularLocation gptkb:cell_membrane
cytosol
gptkbp:UniProtID gptkb:P63000
gptkbp:bfsParent gptkb:RAC
gptkbp:bfsLayer 6