|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:PDGF-A
gptkb:PDGF1
gptkb:platelet-derived_growth_factor_alpha_polypeptide
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:glioblastoma
atherosclerosis
fibrosis
|
|
gptkbp:biologicalProcess
|
cell proliferation
embryonic development
signal transduction
growth factor activity
|
|
gptkbp:discoveredBy
|
gptkb:S._Aaronson
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodes
|
gptkb:platelet-derived_growth_factor_A_chain
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000197461
5154
|
|
gptkbp:expressedIn
|
platelets
endothelial cells
smooth muscle cells
|
|
gptkbp:formsHeterodimerWith
|
gptkb:PDGFA
gptkb:PDGFB
|
|
gptkbp:fullName
|
gptkb:platelet_derived_growth_factor_subunit_A
|
|
gptkbp:function
|
wound healing
angiogenesis
cell division
cell growth
|
|
gptkbp:HGNC_ID
|
HGNC:8806
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PDGFA
|
|
gptkbp:length
|
211
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
gptkb:7p22
|
|
gptkbp:molecularWeight
|
24 kDa
|
|
gptkbp:OMIM
|
190040
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Pdgfa
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:platelet-derived_growth_factor_family
|
|
gptkbp:recipient
|
gptkb:PDGFRA
gptkb:PDGFRB
|
|
gptkbp:RefSeq
|
NM_002607
NP_002598
|
|
gptkbp:UniProtID
|
P04085
|
|
gptkbp:bfsParent
|
gptkb:PDGFRB
gptkb:Platelet-derived_growth_factor
|
|
gptkbp:bfsLayer
|
6
|