|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:FLJ12858
gptkb:PDGF2
gptkb:c-sis
gptkb:SIS
|
|
gptkbp:associatedWith
|
gptkb:idiopathic_basal_ganglia_calcification
gptkb:glioblastoma
gptkb:dermatofibrosarcoma_protuberans
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell migration
growth factor activity
blood vessel development
|
|
gptkbp:discoveredBy
|
gptkb:Reddy_EP_et_al.
|
|
gptkbp:encodes
|
gptkb:platelet-derived_growth_factor_subunit_B_protein
|
|
gptkbp:Entrez_Gene_ID
|
5155
ENSG00000100311
|
|
gptkbp:expressedIn
|
endothelial cells
fibroblasts
smooth muscle cells
|
|
gptkbp:fullName
|
gptkb:platelet_derived_growth_factor_subunit_B
|
|
gptkbp:function
|
growth factor activity
receptor binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0001525
GO:0008083
GO:0008284
|
|
gptkbp:hasTranscriptVariant
|
NM_002608.3
NM_033016.2
|
|
gptkbp:HGNC_ID
|
HGNC:8806
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PDGFB
|
|
gptkbp:involvedIn
|
cell proliferation
embryonic development
wound healing
angiogenesis
|
|
gptkbp:length
|
241 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:22q13.1
chromosome 22
|
|
gptkbp:mutationAssociatedWith
|
gptkb:familial_brain_calcification
oncogenic transformation
|
|
gptkbp:OMIM
|
190040
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Pdgfb
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:platelet-derived_growth_factor_family
|
|
gptkbp:recipient
|
gptkb:PDGFRA
gptkb:PDGFRB
|
|
gptkbp:UniProtID
|
P01127
|
|
gptkbp:bfsParent
|
gptkb:PDGFRB
gptkb:Platelet-derived_growth_factor
|
|
gptkbp:bfsLayer
|
6
|