gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
gptkb:Transformation-related_protein_53
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gptkbp:associatedWith
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gptkb:Li-Fraumeni_syndrome
Various cancers
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gptkbp:database
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gptkb:UniProt
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gptkbp:Entrez_Gene_ID
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7157
ENSG00000141510
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gptkbp:function
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Acts as a tumor suppressor in many tumor types
Involved in DNA repair
Involved in apoptosis
Involved in senescence
Regulates cell cycle
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gptkbp:gene
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gptkb:TP53
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gptkbp:GO
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gptkb:GO:0008285
GO:0005634
GO:0003677
GO:0003700
GO:0006977
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gptkbp:hasIsoform
|
12
|
gptkbp:HGNC_ID
|
11998
|
https://www.w3.org/2000/01/rdf-schema#label
|
P23763
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gptkbp:InterPro
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gptkb:IPR002117
gptkb:IPR011615
IPR010991
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gptkbp:KEGGID
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gptkb:hsa:7157
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gptkbp:locatedOnChromosome
|
17p13.1
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gptkbp:molecularWeight
|
43903 Da
|
gptkbp:mutationAssociatedWith
|
R282W
R175H
R248Q
R273H
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gptkbp:name
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gptkb:P53_HUMAN
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gptkbp:OMIM
|
191170
|
gptkbp:organism
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gptkb:Homo_sapiens
9606
|
gptkbp:PDB
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gptkb:2OCJ
gptkb:3KMD
gptkb:4HJE
1TUP
5XVK
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gptkbp:protein_name
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gptkb:Cellular_tumor_antigen_p53
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gptkbp:proteinFamily
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gptkb:PF00870
|
gptkbp:Reactome
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gptkb:R-HSA-69563
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gptkbp:refersTo
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Tumor protein p53
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gptkbp:RefSeq
|
NP_000537.3
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gptkbp:sequence
|
393
|
gptkbp:status
|
Reviewed
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gptkbp:subcellularLocation
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gptkb:Mitochondrion
gptkb:Nucleus
gptkb:Cytoplasm
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gptkbp:UniGene
|
Hs.476226
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gptkbp:UniProtID
|
gptkb:P23763
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gptkbp:bfsParent
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gptkb:VAMP1
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gptkbp:bfsLayer
|
7
|