|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Catabolin
gptkb:Endogenous_pyrogen
gptkb:IL-1_beta
gptkb:Leukocytic_pyrogen
gptkb:Lymphocyte_activating_factor
gptkb:Mononuclear_cell_factor
|
|
gptkbp:associatedWith
|
gptkb:Autoinflammatory_diseases
gptkb:Osteoarthritis
Rheumatoid arthritis
|
|
gptkbp:biologicalProcess
|
inflammatory response
|
|
gptkbp:cellularComponent
|
extracellular space
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:HGNC
gptkb:PDB
gptkb:UniProt
gptkb:Ensembl
gptkb:Reactome
gptkb:KEGG
|
|
gptkbp:disulfideBond
|
Yes
|
|
gptkbp:function
|
gptkb:Inflammatory_response
Cytokine activity
|
|
gptkbp:gene
|
gptkb:IL1B
|
|
gptkbp:goMolecularFunction
|
cytokine activity
|
|
gptkbp:hasIsoform
|
1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P03951
|
|
gptkbp:locatedOnChromosome
|
2q14
|
|
gptkbp:molecularWeight
|
30.7 kDa
|
|
gptkbp:name
|
gptkb:Interleukin-1_beta
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Il1b
rat Il1b
|
|
gptkbp:pathway
|
gptkb:Cytokine-cytokine_receptor_interaction
gptkb:Toll-like_receptor_signaling_pathway
gptkb:NOD-like_receptor_signaling_pathway
|
|
gptkbp:PDB
|
1I1B
2I1B
3O4O
|
|
gptkbp:postTranslationalModification
|
Proteolytic cleavage
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequence
|
269
|
|
gptkbp:signalPeptide
|
Yes
|
|
gptkbp:structure
|
Monomer
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:taxonId
|
9606
|
|
gptkbp:tissue_specificity
|
gptkb:Leukocytes
Monocytes
Macrophages
|
|
gptkbp:UniProtID
|
gptkb:P03951
|
|
gptkbp:bfsParent
|
gptkb:FXI
gptkb:F11_gene
gptkb:factor_XIa
|
|
gptkbp:bfsLayer
|
7
|