| gptkbp:instanceOf | gptkb:disease gptkb:musculoskeletal_disorder
 
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                                | gptkbp:affects | joints multiple joints
 one joint
 
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                                | gptkbp:alsoKnownAs | degenerative joint disease 
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                                | gptkbp:cause | cartilage degeneration 
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                                | gptkbp:commonIn | hands spine
 hips
 knees
 
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                                | gptkbp:complication | gptkb:disability chronic pain
 decreased mobility
 
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                                | gptkbp:diagnosedBy | gptkb:X-rays clinical evaluation
 MRI
 
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                                | gptkbp:differentialDiagnosis | gptkb:psoriatic_arthritis gout
 rheumatoid arthritis
 
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                                | gptkbp:field | orthopedics rheumatology
 
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                                | gptkbp:firstDescribed | gptkb:William_Heberden 1803
 
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                                | gptkbp:hasNoCure | true 
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                                | gptkbp:ICD-10_code | M15-M19 
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                                | gptkbp:MeSH_ID | D010003 
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                                | gptkbp:OMIM | 165720 
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                                | gptkbp:prevalence | affects millions worldwide most common form of arthritis
 
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                                | gptkbp:progression | gradual 
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                                | gptkbp:riskFactor | age genetics
 obesity
 female sex
 joint injury
 repetitive stress on joint
 
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                                | gptkbp:symptom | joint pain joint stiffness
 joint swelling
 crepitus
 loss of flexibility
 
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                                | gptkbp:treatment | gptkb:exercise gptkb:NSAIDs
 physical therapy
 weight loss
 joint replacement surgery
 pain relievers
 assistive devices
 corticosteroid injections
 
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                                | gptkbp:bfsParent | gptkb:Glucosamine gptkb:The_Knee
 gptkb:OAs
 gptkb:P39059
 gptkb:P03951
 gptkb:Knee
 gptkb:Mesenchymal_Stem_Cell_Therapy
 gptkb:Stem_Cell_Therapy
 
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                                | gptkbp:bfsLayer | 8 
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                                | https://www.w3.org/2000/01/rdf-schema#label | Osteoarthritis 
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