|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:IL-1_beta
IL-1B
IL1F2
pro-interleukin-1-beta
|
|
gptkbp:alternativeSplicing
|
no
|
|
gptkbp:approvedBy
|
interleukin 1 beta
|
|
gptkbp:approvedSymbol
|
gptkb:IL1B
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:type_2_diabetes
rheumatoid arthritis
autoinflammatory syndromes
|
|
gptkbp:biologicalProcess
|
immune response
inflammatory response
cytokine activity
interleukin-1 receptor binding
|
|
gptkbp:cellularComponent
|
extracellular space
|
|
gptkbp:chromosomeArm
|
2q14
|
|
gptkbp:encodes
|
interleukin-1 beta protein
|
|
gptkbp:Entrez_Gene_ID
|
3553
ENSG00000125538
GC02M113597
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
monocytes
|
|
gptkbp:fullName
|
interleukin 1 beta
|
|
gptkbp:function
|
pro-inflammatory cytokine
|
|
gptkbp:HGNC_ID
|
HGNC:5992
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL1B
|
|
gptkbp:involvedIn
|
immune response
inflammatory response
|
|
gptkbp:length
|
269 amino acids
|
|
gptkbp:locatedOnChromosome
|
2
|
|
gptkbp:molecularWeight
|
30.7 kDa
|
|
gptkbp:OMIM
|
147720
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Il1b
|
|
gptkbp:PDB
|
2I1B
3O4O
1ITB
4DEP
|
|
gptkbp:proteinFamily
|
interleukin 1 family
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
differentiation
fever
inflammation
|
|
gptkbp:UniProtID
|
P01584
|
|
gptkbp:bfsParent
|
gptkb:human_chromosome_2
gptkb:P03951
|
|
gptkbp:bfsLayer
|
8
|