Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
gptkb:immune_system_disorder |
| gptkbp:affects |
gptkb:skin
gastrointestinal tract eyes joints immune system serosal membranes |
| gptkbp:canBe |
hereditary
sporadic |
| gptkbp:cause |
gptkb:amyloidosis
organ damage |
| gptkbp:causedBy |
dysregulation of innate immune system
|
| gptkbp:characterizedBy |
recurrent episodes of inflammation
|
| gptkbp:diagnosedBy |
clinical evaluation
genetic testing |
| gptkbp:distinctFrom |
autoimmune diseases
autoimmune diseases by lack of antigen-specific T cells autoimmune diseases by lack of high-titer autoantibodies |
| gptkbp:example |
gptkb:Behçet's_disease
gptkb:Familial_Mediterranean_fever gptkb:Still's_disease gptkb:Blau_syndrome Cryopyrin-associated periodic syndromes Hyper-IgD syndrome PFAPA syndrome TRAPS |
| gptkbp:fieldOfStudy |
immunology
rheumatology |
| gptkbp:firstDescribed |
late 20th century
|
| gptkbp:relatedTo |
gptkb:MEFV_gene
gptkb:TNFRSF1A_gene genetic mutations NLRP3 gene |
| gptkbp:studiedBy |
rheumatologists
immunologists |
| gptkbp:symptom |
fever
abdominal pain joint pain chest pain rash |
| gptkbp:treatment |
corticosteroids
biologic agents colchicine IL-1 inhibitors |
| gptkbp:bfsParent |
gptkb:P03951
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Autoinflammatory diseases
|