FXI

URI: https://gptkb.org/entity/FXI
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:thrombin
gptkb:factor_XIIa
gptkbp:alternativeName gptkb:PTA
gptkb:plasma_thromboplastin_antecedent
gptkbp:associatedWith gptkb:FXI_deficiency
thrombosis
gptkbp:cleavage gptkb:thrombin
gptkb:factor_XIIa
gptkbp:deficiencyCauses gptkb:hemophilia_C
gptkbp:discoveredBy gptkb:Oscar_Ratnoff
gptkbp:discoveredIn 1953
gptkbp:EC_number 3.4.21.27
gptkbp:fullName gptkb:Coagulation_factor_XI
gptkbp:function blood coagulation
gptkbp:gene F11
https://www.w3.org/2000/01/rdf-schema#label FXI
gptkbp:location gptkb:chromosome_4q35
gptkbp:molecularWeight 160 kDa
gptkbp:OMIM 264900
gptkbp:PDB 1XX9
2F83
gptkbp:producedBy liver
gptkbp:role intrinsic pathway of coagulation
gptkbp:species gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:structure homodimer
gptkbp:substrate gptkb:antithrombin
gptkb:C1-inhibitor
gptkbp:UniProtID gptkb:P03951
gptkbp:bfsParent gptkb:Air_Iceland_Connect
gptkbp:bfsLayer 6