Neurotrophic tyrosine kinase receptor type 2

URI: https://gptkb.org/entity/Neurotrophic_tyrosine_kinase_receptor_type_2
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alsoKnownAs gptkb:TrkB
gptkb:NTRK2
gptkbp:binds gptkb:brain-derived_neurotrophic_factor
gptkb:neurotrophin-3
gptkb:neurotrophin-4
gptkbp:encodedBy gptkb:NTRK2_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000148053
gptkbp:expressedIn brain
central nervous system
gptkbp:function receptor for neurotrophins
gptkbp:hasIsoform gptkb:TrkB-FL
gptkb:TrkB-T1
gptkb:TrkB-T2
gptkbp:HGNC_ID 8032
https://www.w3.org/2000/01/rdf-schema#label Neurotrophic tyrosine kinase receptor type 2
gptkbp:involvedIn gptkb:synaptic_plasticity
cell survival
differentiation
neuronal development
memory formation
gptkbp:locatedOnChromosome gptkb:chromosome_9
gptkbp:memberOf gptkb:tyrosine_kinase_receptor_family
gptkbp:mutationAssociatedWith gptkb:cancer
neurodevelopmental disorders
gptkbp:OMIM 600456
gptkbp:phosphorylates tyrosine residues
gptkbp:target cancer therapies
antidepressant drugs
gptkbp:UniProtID gptkb:Q16620
gptkbp:bfsParent gptkb:TrkB
gptkbp:bfsLayer 7