|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Breast_cancer_type_1_susceptibility_protein
|
|
gptkbp:associatedWith
|
hereditary breast and ovarian cancer
|
|
gptkbp:domain
|
gptkb:BRCT_domain
RING finger domain
|
|
gptkbp:encodedBy
|
gptkb:BRCA1_gene
|
|
gptkbp:Entrez_Gene_ID
|
672
|
|
gptkbp:function
|
DNA repair
tumor suppression
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NP 006112.2
|
|
gptkbp:interactsWith
|
gptkb:CHEK2
gptkb:BARD1
gptkb:PALB2
gptkb:p53
gptkb:RAD51
ATM
|
|
gptkbp:length
|
1863 amino acids
|
|
gptkbp:locatedOnChromosome
|
17q21.31
|
|
gptkbp:molecularWeight
|
207 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased cancer risk
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
NP_001100847.1
NP_033898.2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:refersTo
|
human protein sequence
|
|
gptkbp:RefSeq
|
gptkb:NP_006112.2
|
|
gptkbp:sequenceStatus
|
reviewed
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P38398
|
|
gptkbp:bfsParent
|
gptkb:P04234
|
|
gptkbp:bfsLayer
|
8
|