Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
DNA damage response
|
gptkbp:discoveredBy |
Sue J. Bork
|
gptkbp:firstDescribed |
1995
|
gptkbp:foundIn |
gptkb:BRCA1_protein
53BP1 protein MDC1 protein |
gptkbp:function |
protein-protein interaction
phosphopeptide binding |
gptkbp:GO_term |
GO:0005515
|
https://www.w3.org/2000/01/rdf-schema#label |
BRCT domain
|
gptkbp:InterPro |
IPR001357
|
gptkbp:length |
~90-100 amino acids
|
gptkbp:mutationAssociatedWith |
gptkb:cancer
|
gptkbp:namedAfter |
BRCA1 C Terminus
|
gptkbp:presentIn |
eukaryotes
some prokaryotes |
gptkbp:proteinFamily |
PF00533
PS50172 |
gptkbp:SMART |
SM00292
|
gptkbp:structure |
alpha/beta fold
tandem repeat |
gptkbp:UniProtID |
KW-1017
|
gptkbp:bfsParent |
gptkb:Ect2
gptkb:BRCA1_gene gptkb:TopBP1 gptkb:Brca1_(Mus_musculus) gptkb:BARD1 gptkb:BRCA1_DNA_repair_associated gptkb:BRCA1_protein gptkb:mouse_Brca1 |
gptkbp:bfsLayer |
7
|