BRCT domain

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instance_of gptkb:protein
gptkbp:conservation eukaryotes
gptkbp:has_function DNA damage response
https://www.w3.org/2000/01/rdf-schema#label BRCT domain
gptkbp:is_analyzed_in structural biology
gptkbp:is_associated_with gptkb:Oncology
ovarian cancer
genetic mutations
gptkbp:is_characterized_by two BRCT motifs
gptkbp:is_essential_for homologous recombination
gptkbp:is_examined_in clinical trials
gptkbp:is_found_in gptkb:BRCA1_protein
PTEN protein
gptkbp:is_involved_in cell cycle regulation
signal transduction pathways
gptkbp:is_linked_to tumor suppressor genes
gptkbp:is_part_of protein-protein interactions
DNA repair proteins
gptkbp:is_recognized_by genomic studies
gptkbp:is_related_to DNA repair mechanisms
gptkbp:is_studied_in cancer research
gptkbp:is_targeted_at therapeutic agents
gptkbp:is_utilized_in biomarker development
gptkbp:knockouts phosphopeptides
gptkbp:bfsParent gptkb:BARD1_protein
gptkbp:bfsLayer 8