|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:collagenase-1
|
|
gptkbp:associatedWith
|
chronic obstructive pulmonary disease
fibrosis
tumor invasion
|
|
gptkbp:discoveredBy
|
gptkb:G._Murphy_et_al.
|
|
gptkbp:encodes
|
gptkb:interstitial_collagenase
|
|
gptkbp:Entrez_Gene_ID
|
4312
|
|
gptkbp:enzymeClassification
|
EC 3.4.24.7
|
|
gptkbp:expressedIn
|
macrophages
fibroblasts
|
|
gptkbp:fullName
|
gptkb:matrix_metallopeptidase_1
|
|
gptkbp:function
|
degradation of extracellular matrix
|
|
gptkbp:HGNC_ID
|
HGNC:7155
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MMP1
|
|
gptkbp:inhibitedBy
|
gptkb:tissue_inhibitors_of_metalloproteinases_(TIMPs)
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q22.3
|
|
gptkbp:OMIM
|
120353
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:proteinFamily
|
gptkb:matrix_metalloproteinases
|
|
gptkbp:regulates
|
cytokines
growth factors
|
|
gptkbp:relatedTo
|
gptkb:cancer
arthritis
tissue remodeling
|
|
gptkbp:substrate
|
gptkb:collagen_type_I
gptkb:collagen_type_II
gptkb:collagen_type_III
|
|
gptkbp:UniProtID
|
P03956
|
|
gptkbp:bfsParent
|
gptkb:EGR1
|
|
gptkbp:bfsLayer
|
6
|