Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:MMP-1
matrix metalloproteinase-1 |
| gptkbp:catalyzes |
degradation of interstitial collagens (types I, II, III)
|
| gptkbp:cofactor |
zinc
calcium |
| gptkbp:discoveredBy |
G.O. Gross
|
| gptkbp:discoveredIn |
1962
|
| gptkbp:EC_number |
3.4.24.7
|
| gptkbp:family |
gptkb:matrix_metalloproteinases
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
extracellular matrix remodeling
|
| gptkbp:gene |
gptkb:MMP1
|
| https://www.w3.org/2000/01/rdf-schema#label |
interstitial collagenase
|
| gptkbp:involvedIn |
arthritis
tissue repair tumor invasion |
| gptkbp:regulates |
gptkb:tissue_inhibitors_of_metalloproteinases_(TIMPs)
|
| gptkbp:structure |
contains catalytic domain
contains hemopexin-like domain |
| gptkbp:bfsParent |
gptkb:MMP1
|
| gptkbp:bfsLayer |
7
|