gptkbp:instanceOf
|
gptkb:gene
|
gptkbp:alternativeSplicing
|
yes
|
gptkbp:associatedWith
|
immune response
|
gptkbp:biologicalProcess
|
stress-induced ligand for NKG2D
|
gptkbp:discoveredIn
|
1994
|
gptkbp:encodes
|
MICA protein
|
gptkbp:Entrez_Gene_ID
|
4276
ENSG00000204516
|
gptkbp:expressedIn
|
endothelial cells
fibroblasts
epithelial cells
|
gptkbp:fullName
|
MHC class I polypeptide-related sequence A
|
gptkbp:hasPolymorphism
|
true
|
gptkbp:HGNC_ID
|
7090
|
https://www.w3.org/2000/01/rdf-schema#label
|
MICA gene
|
gptkbp:involves
|
gptkb:cancer
autoimmune diseases
transplant rejection
|
gptkbp:length
|
383 amino acids
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
6p21.33
|
gptkbp:memberOf
|
gptkb:major_histocompatibility_complex
|
gptkbp:OMIM
|
600179
|
gptkbp:orthologInMouse
|
no direct ortholog
|
gptkbp:product
|
transmembrane glycoprotein
|
gptkbp:proteinFamily
|
gptkb:MHC_class_I_family
|
gptkbp:proteinWeight
|
43 kDa
|
gptkbp:recognizedBy
|
NKG2D receptor
|
gptkbp:relatedTo
|
gptkb:HLA_genes
gptkb:MICB_gene
|
gptkbp:UniProtID
|
Q29983
|
gptkbp:variant
|
gptkb:primary_biliary_cirrhosis
gptkb:Behçet's_disease
gptkb:systemic_lupus_erythematosus
gptkb:Crohn's_disease
gptkb:Hashimoto's_thyroiditis
gptkb:Sjögren's_syndrome
gptkb:systemic_sclerosis
gptkb:graft-versus-host_disease
colorectal cancer
Graves' disease
multiple sclerosis
type 1 diabetes
ulcerative colitis
psoriasis
rheumatoid arthritis
hepatocellular carcinoma
gastric cancer
celiac disease
ankylosing spondylitis
|
gptkbp:bfsParent
|
gptkb:6p21.3
|
gptkbp:bfsLayer
|
7
|