|
gptkbp:instanceOf
|
autoimmune disease
systemic disease
|
|
gptkbp:affects
|
exocrine glands
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
rheumatoid arthritis
|
|
gptkbp:cause
|
leukemia
fatigue
joint pain
peripheral neuropathy
skin rashes
kidney involvement
lung involvement
swelling of salivary glands
vaginal dryness
|
|
gptkbp:characterizedBy
|
dry mouth
dry eyes
|
|
gptkbp:commonIn
|
gptkb:women
|
|
gptkbp:complication
|
leukemia
peripheral neuropathy
vasculitis
renal tubular acidosis
interstitial lung disease
|
|
gptkbp:diagnosedBy
|
gptkb:Schirmer's_test
gptkb:anti-SSA_antibody
gptkb:anti-SSB_antibody
salivary gland biopsy
|
|
gptkbp:field
|
rheumatology
|
|
gptkbp:firstDescribed
|
1933
|
|
gptkbp:hasAutoantibody
|
gptkb:anti-La/SSB
gptkb:anti-Ro/SSA
gptkb:antinuclear_antibody
gptkb:rheumatoid_factor
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sjögren's syndrome
|
|
gptkbp:ICD-10_code
|
M35.0
|
|
gptkbp:MeSH_ID
|
D012859
|
|
gptkbp:namedAfter
|
gptkb:Henrik_Sjögren
|
|
gptkbp:OMIM
|
270150
|
|
gptkbp:prevalence
|
0.1% to 4% of population
|
|
gptkbp:riskFactor
|
genetic predisposition
other autoimmune diseases
female sex
|
|
gptkbp:symptom
|
gptkb:keratoconjunctivitis_sicca
xerostomia
|
|
gptkbp:treatment
|
gptkb:pilocarpine
corticosteroids
immunosuppressants
eye drops
cevimeline
hydroxychloroquine
|
|
gptkbp:typicalOnsetAge
|
40-60 years
|
|
gptkbp:bfsParent
|
gptkb:Primary_Biliary_Cirrhosis
gptkb:Schur's_syndrome
|
|
gptkbp:bfsLayer
|
6
|