|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
autoimmune diseases
transplant rejection
|
|
gptkbp:binds
|
peptides
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:encodedBy
|
MHC locus
|
|
gptkbp:expressedIn
|
cell surface
|
|
gptkbp:foundIn
|
jawed vertebrates
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasPolymorphism
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MHC class I family
|
|
gptkbp:includes
|
gptkb:H-2D
gptkb:H-2K
gptkb:H-2L
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
gptkb:HLA-E
gptkb:HLA-F
gptkb:HLA-G
|
|
gptkbp:involvedIn
|
adaptive immune response
immune surveillance
|
|
gptkbp:orthologIn
|
gptkb:H-2_complex_in_mice
RT1 in rats
|
|
gptkbp:peptideLength
|
8-10 amino acids
|
|
gptkbp:presentIn
|
all nucleated cells
|
|
gptkbp:recognizedBy
|
gptkb:CD8+_T_cells
gptkb:NK_cell_receptors
|
|
gptkbp:requires
|
self/non-self discrimination
|
|
gptkbp:structure
|
heterodimer
heavy chain and beta-2 microglobulin
|
|
gptkbp:bfsParent
|
gptkb:HLAG
gptkb:MHC_class_I-related_protein_1
gptkb:MR1_protein
gptkb:MICB
gptkb:CD1_family
gptkb:HFE_gene
gptkb:HLA-E
gptkb:MICA_gene
gptkb:MICB_gene
|
|
gptkbp:bfsLayer
|
8
|