Behçet's disease

GPTKB entity

Statements (42)
Predicate Object
gptkbp:instanceOf autoimmune disease
systemic vasculitis
gptkbp:affects both sexes
gptkbp:alsoKnownAs Behçet syndrome
gptkbp:cause unknown
gptkbp:complication stroke
blindness
thrombosis
aneurysm
gptkbp:diagnosedBy clinical criteria
pathergy test
gptkbp:field dermatology
ophthalmology
rheumatology
gptkbp:firstDescribed 1937
gptkbp:hasNoCure true
gptkbp:hasOrphanetID ORPHA:109
https://www.w3.org/2000/01/rdf-schema#label Behçet's disease
gptkbp:ICD-10_code M35.2
gptkbp:MeSH_ID D001523
gptkbp:mortalityRate low with treatment
gptkbp:namedAfter Hulusi Behçet
gptkbp:OMIM 109650
gptkbp:onset 20-40 years
gptkbp:prevalence rare in North America
higher in Silk Road countries
gptkbp:riskFactor genetic predisposition
HLA-B51 allele
gptkbp:symptom arthritis
uveitis
skin lesions
gastrointestinal involvement
oral ulcers
genital ulcers
neurological involvement
vascular inflammation
gptkbp:treatment corticosteroids
immunosuppressants
colchicine
TNF inhibitors
gptkbp:bfsParent gptkb:Rosemary_Sutcliff
gptkbp:bfsLayer 6