Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:affects |
gptkb:skincare_product
blood vessels connective tissue |
| gptkbp:associated_with |
genetic factors
environmental triggers anti-Scl-70 antibodies anti-centromere antibodies |
| gptkbp:caused_by |
immune system dysfunction
|
| gptkbp:complications |
pulmonary hypertension
interstitial lung disease renal crisis esophageal dysmotility |
| gptkbp:historical_context |
first described in the 18th century
named after the Greek words for 'hard' and 'skin' |
| https://www.w3.org/2000/01/rdf-schema#label |
systemic sclerosis
|
| gptkbp:is_popular_in |
more common in women
onset typically between ages 30 and 50 |
| gptkbp:research_focus |
quality of life
biomarkers treatment options pathogenesis |
| gptkbp:social_responsibility |
blood tests
imaging studies clinical evaluation |
| gptkbp:symptoms |
gptkb:Raynaud's_phenomenon
fatigue joint pain shortness of breath thickened skin |
| gptkbp:treatment |
physical therapy
corticosteroids immunosuppressants antifibrotic agents |
| gptkbp:type |
gptkb:healthcare_organization
|
| gptkbp:bfsParent |
gptkb:rituximab
|
| gptkbp:bfsLayer |
4
|