Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
phosphorylation
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:downstreamOf |
transcription factors
|
| gptkbp:enzymeClassification |
serine/threonine kinase
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
gptkb:Mitogen-activated_protein_kinase_family
|
| gptkbp:function |
signal transduction
regulation of cellular processes |
| gptkbp:GO_term |
GO:0000165
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAPK family
|
| gptkbp:involvedIn |
apoptosis
cell differentiation cell proliferation stress response |
| gptkbp:member |
gptkb:JNK
gptkb:p38_MAPK gptkb:ERK gptkb:ERK5 |
| gptkbp:pathway |
gptkb:MAPK/ERK_pathway
gptkb:MAPK/JNK_pathway gptkb:MAPK/p38_pathway |
| gptkbp:significance |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:upregulatedBy |
gptkb:MAPKK
gptkb:MAPKKK |
| gptkbp:bfsParent |
gptkb:mitogen-activated_protein_kinase
|
| gptkbp:bfsLayer |
6
|