|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
gptkb:JNK1
gptkb:JNK2
gptkb:JNK3
|
|
gptkbp:alsoKnownAs
|
JNK-activated protein kinase
MAPKAP kinase 7
MAPKAP-K2
|
|
gptkbp:associatedWith
|
gptkb:MAP_kinase_signaling_pathway
|
|
gptkbp:discoveredBy
|
researchers in the late 1990s
|
|
gptkbp:encodes
|
Mitogen-activated protein kinase-activated protein kinase 7
|
|
gptkbp:Entrez_Gene_ID
|
9261
ENSG00000104880
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
signal transduction
protein serine/threonine kinase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6885
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPKAPK7
|
|
gptkbp:involvedIn
|
apoptosis regulation
transcription regulation
cellular response to stress
stress-activated protein kinase signaling cascade
|
|
gptkbp:length
|
422 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Mapkapk7
|
|
gptkbp:phosphorylates
|
gptkb:ATF2
gptkb:HSP27
gptkb:c-Jun
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NM_145331
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
cell survival
gene expression
inflammatory response
|
|
gptkbp:relatedTo
|
gptkb:MAPK10
gptkb:MAPK9
gptkb:MAPK8
|
|
gptkbp:significance
|
potential role in cancer
potential role in neurodegenerative diseases
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
O15264
|
|
gptkbp:bfsParent
|
gptkb:RAF1_gene
|
|
gptkbp:bfsLayer
|
7
|