JAK-1

URI: https://gptkb.org/entity/JAK-1
GPTKB entity
Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:JAK1
gptkb:Janus_kinase_1
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
gptkbp:discoveredIn 1992
gptkbp:encodedBy gptkb:JAK1_gene
gptkbp:enzymeClassification EC 2.7.10.2
gptkbp:fullName gptkb:Janus_kinase_1
gptkbp:function gptkb:receptor_tyrosine_kinase
signal transduction
gptkbp:gene gptkb:JAK1
https://www.w3.org/2000/01/rdf-schema#label JAK-1
gptkbp:interactsWith gptkb:STAT1
gptkb:interferon_receptors
gptkb:STAT3
gptkb:STAT5
interleukin receptors
gptkbp:involvedIn gptkb:JAK-STAT_signaling_pathway
gptkbp:locatedOnChromosome 1p31.3
gptkbp:molecularWeight approximately 130 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:targetOfDrug gptkb:tofacitinib
gptkb:upadacitinib
gptkb:baricitinib
gptkbp:UniProtID gptkb:P23458
gptkbp:bfsParent gptkb:JAK1
gptkbp:bfsLayer 8