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gptkbp:instanceOf
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gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:G25K
CDC42Hs
cell division control protein 42 homolog
|
|
gptkbp:associatedWith
|
gptkb:cancer
immunodeficiency
neurodevelopmental disorders
|
|
gptkbp:biologicalProcess
|
GTPase activity
|
|
gptkbp:discoveredIn
|
gptkb:yeast
|
|
gptkbp:encodedBy
|
CDC42 gene
|
|
gptkbp:foundIn
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gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
cell migration
regulation of cell cycle
cell polarity
cell morphology
actin cytoskeleton organization
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cdc42
|
|
gptkbp:interactsWith
|
gptkb:PAK1
gptkb:WASP
gptkb:DOCK9
gptkb:GDI1
gptkb:IQGAP1
MRCK alpha
Par3
Par6
|
|
gptkbp:length
|
191 amino acids
|
|
gptkbp:locatedOnChromosome
|
1p36.12
|
|
gptkbp:memberOf
|
gptkb:Rho_GTPase_family
|
|
gptkbp:orthologIn
|
gptkb:Saccharomyces_cerevisiae
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
|
|
gptkbp:regulates
|
gptkb:GDIs_(guanine_nucleotide_dissociation_inhibitors)
gptkb:GAPs_(GTPase-activating_proteins)
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
signal transduction
cell division
endocytosis
exocytosis
filopodia formation
|
|
gptkbp:structure
|
gptkb:GTP-binding_domain
|
|
gptkbp:subcellularLocation
|
gptkb:Golgi_apparatus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P60953
|
|
gptkbp:bfsParent
|
gptkb:Rho_family
|
|
gptkbp:bfsLayer
|
6
|