|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:IGF-II
gptkb:Somatomedin-A
Multiplication-stimulating activity
|
|
gptkbp:associatedWith
|
gptkb:Wilms_tumor
gptkb:cancer
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
|
|
gptkbp:biologicalProcess
|
Cell proliferation
Fetal development
Cell growth
Regulation of glucose metabolism
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:HGNC
gptkb:UniProt
|
|
gptkbp:discoveredIn
|
1978
|
|
gptkbp:Entrez_Gene_ID
|
3481
ENSG00000167244
|
|
gptkbp:expressedIn
|
gptkb:Placenta
Liver
Muscle
Fetal tissues
|
|
gptkbp:fullName
|
gptkb:Insulin-like_growth_factor_II
|
|
gptkbp:function
|
Growth factor
Mitogen
|
|
gptkbp:gene
|
gptkb:IGF2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IGF2 HUMAN
|
|
gptkbp:imprint
|
Yes
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:molecularWeight
|
20.1 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:IGF2_MOUSE
gptkb:IGF2_RAT
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Insulin_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1IGL
1QTY
|
|
gptkbp:postTranslationalModification
|
Disulfide bond
Glycosylation
|
|
gptkbp:recipient
|
gptkb:INSR
gptkb:IGF2R
gptkb:IGF1R
|
|
gptkbp:RefSeq
|
NP_000604.1
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequence
|
180
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:tissue_specificity
|
Expressed in most tissues, highest in fetal tissues
|
|
gptkbp:UniProtID
|
P01344
|
|
gptkbp:bfsParent
|
gptkb:P08014
|
|
gptkbp:bfsLayer
|
7
|