|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:endometrial_cancer
gptkb:glioblastoma
prostate cancer
|
|
gptkbp:encodes
|
gptkb:PTEN
|
|
gptkbp:Entrez_Gene_ID
|
5728
|
|
gptkbp:essentialGene
|
true
|
|
gptkbp:function
|
lipid phosphatase activity
protein phosphatase activity
|
|
gptkbp:gene
|
gptkb:PTEN
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscript
|
ENST00000457361
ENST00000371953
ENST00000479732
ENST00000458521
ENST00000476043
ENST00000462634
ENST00000489813
|
|
gptkbp:hasYeastOrtholog
|
gptkb:PTC1
|
|
gptkbp:hasZebrafishOrtholog
|
ptena
ptenb
|
|
gptkbp:HGNC_ID
|
9588
|
|
gptkbp:involvedIn
|
gptkb:PI3K/AKT_signaling_pathway
|
|
gptkbp:isImprinted
|
false
|
|
gptkbp:isTumorSuppressor
|
true
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
gptkb:10q23.31
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pten
|
|
gptkbp:product
|
gptkb:Phosphatase_and_tensin_homolog
|
|
gptkbp:RefSeq
|
gptkb:NM_000314
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
cell survival
cell growth
cell migration
|
|
gptkbp:startPoint
|
87863119
87971930
|
|
gptkbp:strand
|
minus
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:HSP90AA1
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000080824
|