|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
MHC class I (in humans)
|
|
gptkbp:binds
|
peptides
|
|
gptkbp:component
|
gptkb:beta-2_microglobulin
alpha chain
|
|
gptkbp:encodedBy
|
gptkb:HLA-A_gene
gptkb:HLA-B_gene
gptkb:HLA-C_gene
|
|
gptkbp:expressedIn
|
all nucleated cells
|
|
gptkbp:foundIn
|
humans
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasPolymorphism
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA class I (in humans)
|
|
gptkbp:importantFor
|
transplant compatibility
|
|
gptkbp:involvedIn
|
immune response
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:notExpressedOn
|
red blood cells
|
|
gptkbp:partOf
|
gptkb:major_histocompatibility_complex
|
|
gptkbp:peptideLength
|
8-10 amino acids
|
|
gptkbp:presentTo
|
gptkb:CD8+_T_cells
|
|
gptkbp:recognizedBy
|
gptkb:natural_killer_cells
cytotoxic T lymphocytes
|
|
gptkbp:role
|
autoimmune diseases
cancer immunology
graft rejection
viral immunity
|
|
gptkbp:structure
|
heterodimer
|
|
gptkbp:subspecies
|
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
gptkb:HLA-E
gptkb:HLA-F
gptkb:HLA-G
|
|
gptkbp:bfsParent
|
gptkb:MHC_class_I
|
|
gptkbp:bfsLayer
|
7
|