|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
autoimmune diseases
immune response
organ transplant compatibility
HLA-B27 related diseases
|
|
gptkbp:discoveredBy
|
gptkb:Jean_Dausset
|
|
gptkbp:discoveredIn
|
1968
|
|
gptkbp:encodes
|
HLA-B protein
|
|
gptkbp:Entrez_Gene_ID
|
3106
ENSG00000234745
|
|
gptkbp:expressedIn
|
all nucleated cells
|
|
gptkbp:function
|
presentation of peptide antigens to T cells
|
|
gptkbp:hasPolymorphism
|
gptkb:HLA-B27
HLA-B*15:02
HLA-B*58:01
HLA-B57
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:4932
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-B gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Stevens-Johnson_syndrome
ankylosing spondylitis
abacavir hypersensitivity
allopurinol hypersensitivity
|
|
gptkbp:OMIM
|
142830
|
|
gptkbp:orthologInMouse
|
H2-K
RT1-A
|
|
gptkbp:partOf
|
gptkb:major_histocompatibility_complex
|
|
gptkbp:product
|
HLA-B heavy chain
|
|
gptkbp:proteinFamily
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:subclassOf
|
gptkb:MHC_class_I_genes
|
|
gptkbp:UniProtID
|
P01889
|
|
gptkbp:bfsParent
|
gptkb:6p21.3
gptkb:HLA_class_I_molecules
gptkb:M343_mutation
|
|
gptkbp:bfsLayer
|
7
|