|
gptkbp:instanceOf
|
T cell subtype
|
|
gptkbp:activatedBy
|
antigen-presenting cells
|
|
gptkbp:alsoKnownAs
|
cytotoxic T lymphocytes
|
|
gptkbp:canBeDepletedBy
|
antibody-mediated depletion
|
|
gptkbp:developedBy
|
thymocytes
|
|
gptkbp:distinctiveFeature
|
effector CD8+ T cells
memory CD8+ T cells
|
|
gptkbp:expressedIn
|
gptkb:CD8_glycoprotein
|
|
gptkbp:firstDescribed
|
gptkb:Peter_Doherty
gptkb:Rolf_Zinkernagel
|
|
gptkbp:foundIn
|
lymphoid organs
peripheral blood
|
|
gptkbp:function
|
kill tumor cells
kill virus-infected cells
produce cytokines
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD8+ T cells
|
|
gptkbp:involves
|
HIV infection
immunotherapy
viral clearance
chronic infections
|
|
gptkbp:marking
|
gptkb:CD3
gptkb:CD8
|
|
gptkbp:measures
|
flow cytometry
|
|
gptkbp:proliferatesInResponseTo
|
gptkb:IL-2
|
|
gptkbp:recognizedBy
|
antigen presented by MHC class I molecules
|
|
gptkbp:requires
|
co-stimulation for activation
|
|
gptkbp:role
|
autoimmune diseases
adaptive immune response
immunological memory
transplant rejection
|
|
gptkbp:secretes
|
gptkb:interferon-gamma
gptkb:perforin
gptkb:granzyme_B
|
|
gptkbp:studiedIn
|
immunology
infectious diseases
oncology
|
|
gptkbp:surfaceProtein
|
gptkb:T_cell_receptor_(TCR)
|
|
gptkbp:bfsParent
|
gptkb:T_cell_receptor_(TCR)
|
|
gptkbp:bfsLayer
|
6
|