HLA-A gene

URI: https://gptkb.org/entity/HLA-A_gene
GPTKB entity
Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeSplicing yes
gptkbp:associatedWith organ transplantation
autoimmune diseases
gptkbp:discoveredIn 1970s
gptkbp:encodes HLA-A protein
gptkbp:Entrez_Gene_ID 3105
ENSG00000206503
gptkbp:expressedIn most nucleated cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function antigen presentation
gptkbp:hasAllele HLA-A*01, HLA-A*02, HLA-A*03, HLA-A*24, HLA-A*26, HLA-A*68, HLA-A*69, HLA-A*80
gptkbp:hasPolymorphism true
gptkbp:hasTranscriptVariant multiple
gptkbp:HGNC_ID HGNC:4931
https://www.w3.org/2000/01/rdf-schema#label HLA-A gene
gptkbp:locatedOn gptkb:chromosome_6
gptkbp:locusType gptkb:6p21.3
gptkbp:memberOf gptkb:major_histocompatibility_complex
gptkb:MHC_class_I_genes
gptkbp:OMIM 142800
gptkbp:orthologIn mouse H2-K gene
gptkbp:product HLA class I histocompatibility antigen, A alpha chain
gptkbp:significance disease susceptibility
tissue typing
gptkbp:UniProtID P01892
gptkbp:bfsParent gptkb:6p21.3
gptkb:HLA_class_I_molecules
gptkbp:bfsLayer 7