|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
HLA-6.2
MHC class I antigen E
|
|
gptkbp:associatedWith
|
infectious diseases
autoimmune diseases
transplantation tolerance
|
|
gptkbp:binds
|
peptides derived from leader sequences of other HLA class I molecules
|
|
gptkbp:encodes
|
HLA-E protein
|
|
gptkbp:Entrez_Gene_ID
|
3133
ENSG00000204525
|
|
gptkbp:expressedIn
|
various human tissues
cell surface
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
inhibits NK cell cytotoxicity
presents peptides to immune cells
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
true
|
|
gptkbp:hasRole
|
immune response
|
|
gptkbp:HGNC_ID
|
HGNC:4932
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-E
|
|
gptkbp:locatedIn
|
gptkb:human_chromosome_6
|
|
gptkbp:memberOf
|
gptkb:major_histocompatibility_complex
gptkb:MHC_class_I_family
|
|
gptkbp:OMIM
|
143010
|
|
gptkbp:orthologIn
|
mouse Qa-1
|
|
gptkbp:recognizedBy
|
gptkb:NK_cell_receptors
CD94/NKG2A receptor
CD94/NKG2C receptor
|
|
gptkbp:structure
|
heterodimer with beta-2 microglobulin
|
|
gptkbp:UniProtID
|
P13747
|
|
gptkbp:bfsParent
|
gptkb:MHC_class_I_molecules
gptkb:chromosome_6p21.31
|
|
gptkbp:bfsLayer
|
7
|