|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:BiP
gptkb:HSPA5
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:encodedBy
|
HSPA5 gene
|
|
gptkbp:family
|
gptkb:heat_shock_protein_70_family
|
|
gptkbp:function
|
protein folding
unfolded protein response
molecular chaperone
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GRP78
|
|
gptkbp:interactsWith
|
gptkb:ATF6
gptkb:IRE1
gptkb:PERK
misfolded proteins
|
|
gptkbp:involvedIn
|
gptkb:virus
cancer progression
apoptosis regulation
cellular stress response
|
|
gptkbp:locatedIn
|
gptkb:endoplasmic_reticulum
|
|
gptkbp:locatedOnChromosome
|
9q33.3
|
|
gptkbp:marking
|
ER stress
|
|
gptkbp:molecularWeight
|
78 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:overexpressedIn
|
various cancers
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:regulates
|
ER stress response
|
|
gptkbp:requires
|
cell survival
|
|
gptkbp:structure
|
ATPase domain
substrate-binding domain
|
|
gptkbp:target
|
anticancer therapy
|
|
gptkbp:UniProtID
|
P11021
|
|
gptkbp:bfsParent
|
gptkb:Bip_(gene)
gptkb:Bip_(protein)
|
|
gptkbp:bfsLayer
|
6
|