Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PEK
EIF2AK3 |
| gptkbp:associatedWith |
Wolcott-Rallison syndrome
|
| gptkbp:biologicalProcess |
protein serine/threonine kinase activity
|
| gptkbp:discoveredBy |
David Ron
|
| gptkbp:encodedBy |
EIF2AK3 gene
|
| gptkbp:enzymeClassification |
EC 2.7.11.1
|
| gptkbp:fullName |
Protein kinase R (PKR)-like endoplasmic reticulum kinase
|
| gptkbp:function |
phosphorylates eIF2α
regulates unfolded protein response |
| gptkbp:gene |
EIF2AK3
|
| gptkbp:HGNC_ID |
3256
|
| https://www.w3.org/2000/01/rdf-schema#label |
PERK
|
| gptkbp:involvedIn |
regulation of translation
cellular response to endoplasmic reticulum stress |
| gptkbp:locatedOnChromosome |
chromosome 2p12
|
| gptkbp:location |
endoplasmic reticulum membrane
|
| gptkbp:OMIM |
604032
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:Q9NZJ5
|
| gptkbp:bfsParent |
gptkb:Bip_(protein)
|
| gptkbp:bfsLayer |
6
|