|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:insulin
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
|
|
gptkbp:catalyzes
|
oxidation of glucose-6-phosphate to 6-phosphoglucono-δ-lactone
|
|
gptkbp:clinicalTrialPhase
|
G6PD test
|
|
gptkbp:cofactor
|
NADP+
|
|
gptkbp:deficiencyAssociatedWith
|
gptkb:anemia
|
|
gptkbp:deficiencyCauses
|
gptkb:G6PD_deficiency
|
|
gptkbp:discoveredBy
|
gptkb:Ernest_Beutler
|
|
gptkbp:EC_number
|
1.1.1.49
|
|
gptkbp:expressedIn
|
erythrocytes
|
|
gptkbp:foundIn
|
gptkb:Bacteria
animals
humans
plants
|
|
gptkbp:fullName
|
gptkb:glucose-6-phosphate_dehydrogenase
|
|
gptkbp:gene
|
gptkb:G6PD
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
G6PDH
|
|
gptkbp:importantFor
|
protects cells from oxidative damage
|
|
gptkbp:inhibitedBy
|
polydatin
dehydroepiandrosterone
|
|
gptkbp:locatedOnChromosome
|
Xq28 (in humans)
|
|
gptkbp:OMIM
|
305900
|
|
gptkbp:pathway
|
gptkb:pentose_phosphate_pathway
|
|
gptkbp:PDB
|
2BH9
|
|
gptkbp:product
|
gptkb:6-phosphoglucono-δ-lactone
NADPH
|
|
gptkbp:regulates
|
allosteric regulation
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:glucose-6-phosphate
|
|
gptkbp:UniProtID
|
P11413
|
|
gptkbp:bfsParent
|
gptkb:P45381
gptkb:glucose-6-phosphate_dehydrogenase
gptkb:G6PD_gene
gptkb:G6PD_protein
gptkb:human_G6PD_protein
|
|
gptkbp:bfsLayer
|
7
|