Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
enzyme deficiency |
| gptkbp:affects |
glucose-6-phosphate dehydrogenase enzyme
|
| gptkbp:cause |
gptkb:chronic_non-spherocytic_hemolytic_anemia
|
| gptkbp:causedBy |
mutation in G6PD gene
|
| gptkbp:complication |
gptkb:acute_hemolytic_anemia
gptkb:neonatal_jaundice |
| gptkbp:detects |
genetic testing
enzyme assay |
| gptkbp:diagnosedBy |
blood test
|
| gptkbp:firstDescribed |
1926
|
| gptkbp:frequency |
over 400 million people worldwide
|
| https://www.w3.org/2000/01/rdf-schema#label |
G6PD deficiency
|
| gptkbp:ICD-10_code |
D55.0
|
| gptkbp:inheritance |
X-linked recessive
|
| gptkbp:MeSH_ID |
D006060
|
| gptkbp:namedAfter |
gptkb:glucose-6-phosphate_dehydrogenase
|
| gptkbp:OMIM |
300908
|
| gptkbp:prevalence |
common in people of African, Mediterranean, and Asian descent
|
| gptkbp:riskFactor |
family history
male sex |
| gptkbp:symptom |
gptkb:anemia
fatigue jaundice |
| gptkbp:treatment |
avoidance of triggers
supportive care during hemolytic episodes |
| gptkbp:triggeredBy |
infections
certain foods (e.g., fava beans) certain medications (e.g., sulfa drugs, antimalarials) |
| gptkbp:bfsParent |
gptkb:anemia
|
| gptkbp:bfsLayer |
5
|