|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:G6PD
gptkb:G6PDH
gptkb:glucose-6-phosphate_dehydrogenase,_cytoplasmic
|
|
gptkbp:associatedWith
|
gptkb:G6PD_deficiency
|
|
gptkbp:biologicalProcess
|
NADPH production
protection against oxidative stress
|
|
gptkbp:cellularComponent
|
cytosol
|
|
gptkbp:cofactor
|
NADP+
|
|
gptkbp:encodedBy
|
gptkb:G6PD_gene
|
|
gptkbp:Entrez_Gene_ID
|
2539
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_1.1.1.49
|
|
gptkbp:fullName
|
gptkb:Glucose-6-phosphate_dehydrogenase
|
|
gptkbp:function
|
catalyzes the first step in the pentose phosphate pathway
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human G6PD protein
|
|
gptkbp:locatedOnChromosome
|
gptkb:Xq28
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
59 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:anemia
gptkb:favism
|
|
gptkbp:OMIM
|
305900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
2BH9
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:product
|
gptkb:6-phosphoglucono-δ-lactone
NADPH
|
|
gptkbp:structure
|
homodimer or homotetramer
|
|
gptkbp:substrate
|
gptkb:glucose-6-phosphate
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
P11413
|
|
gptkbp:bfsParent
|
gptkb:NP_000445.1
|
|
gptkbp:bfsLayer
|
6
|