|
gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:G6P_dehydrogenase
|
|
gptkbp:associatedWith
|
gptkb:G6PD_deficiency
gptkb:anemia
|
|
gptkbp:clinicalTrialPhase
|
G6PD activity assay
|
|
gptkbp:cofactor
|
NADP+
|
|
gptkbp:discoveredBy
|
gptkb:Ernest_Beutler
|
|
gptkbp:discoveredIn
|
1956
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|
gptkbp:EC_number
|
1.1.1.49
|
|
gptkbp:encodedBy
|
gptkb:G6PD_gene
|
|
gptkbp:fullName
|
gptkb:glucose-6-phosphate_dehydrogenase
|
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gptkbp:function
|
catalyzes the first step in the pentose phosphate pathway
converts glucose-6-phosphate to 6-phosphoglucono-δ-lactone
|
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gptkbp:gene
|
gptkb:G6PD
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
G6PD
|
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gptkbp:importantFor
|
protects red blood cells from oxidative damage
|
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gptkbp:inheritance
|
X-linked recessive
|
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gptkbp:locatedOnChromosome
|
gptkb:Xq28
|
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gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:mutationAssociatedWith
|
can cause G6PD deficiency
|
|
gptkbp:OMIM
|
305900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:pathway
|
gptkb:pentose_phosphate_pathway
|
|
gptkbp:PDB
|
2BH9
|
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gptkbp:product
|
gptkb:6-phosphoglucono-δ-lactone
NADPH
|
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gptkbp:structure
|
homodimer
|
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gptkbp:substrate
|
gptkb:glucose-6-phosphate
|
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gptkbp:UniProtID
|
P11413
|
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gptkbp:bfsParent
|
gptkb:NP_000445.1
gptkb:Xq28
|
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gptkbp:bfsLayer
|
6
|