|
gptkbp:instanceOf
|
gptkb:protein
molecular switch
|
|
gptkbp:abbreviation
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
G-protein-coupled receptor
|
|
gptkbp:alternativeName
|
guanine nucleotide-binding protein
|
|
gptkbp:binds
|
guanosine triphosphate
guanosine diphosphate
|
|
gptkbp:composedOf
|
alpha subunit
beta subunit
gamma subunit
|
|
gptkbp:decommissioned
|
hydrolysis of GTP
|
|
gptkbp:discoveredBy
|
gptkb:Martin_Rodbell
gptkb:Alfred_G._Gilman
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:cancer
gptkb:whooping_cough
cholera
|
|
gptkbp:encodedBy
|
gptkb:GNA_genes
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:function
|
transmit signals from outside to inside the cell
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
G-protein
|
|
gptkbp:involvedIn
|
signal transduction
|
|
gptkbp:location
|
inner surface of plasma membrane
|
|
gptkbp:NobelPrizeYear
|
1994
|
|
gptkbp:regulates
|
gptkb:adenylate_cyclase
gptkb:phospholipase_C
ion channels
|
|
gptkbp:relatedTo
|
gptkb:Ras_protein
guanine nucleotide exchange factor
|
|
gptkbp:subclassOf
|
gptkb:G12/13_protein
gptkb:Gi_protein
gptkb:Gq_protein
gptkb:Gs_protein
|
|
gptkbp:type
|
heterotrimeric G-protein
monomeric G-protein
|
|
gptkbp:bfsParent
|
gptkb:ACKR3
|
|
gptkbp:bfsLayer
|
8
|