|
gptkbp:instanceOf
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:protein_kinase_C
gptkb:G_protein-coupled_receptors
phospholipase C beta
diacylglycerol (DAG) production
inositol trisphosphate (IP3) production
|
|
gptkbp:alphaSubunit
|
gptkb:Gαq
|
|
gptkbp:alternativeName
|
GNAQ protein
Gq alpha subunit
Gαq protein
|
|
gptkbp:associatedWith
|
gptkb:Sturge-Weber_syndrome
gptkb:uveal_melanoma
|
|
gptkbp:betaSubunit
|
Gβ
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
GNAQ gene
|
|
gptkbp:function
|
signal transduction
|
|
gptkbp:gammaSubunit
|
Gγ
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Gq protein
|
|
gptkbp:inhibitedBy
|
RGS proteins
|
|
gptkbp:involvedIn
|
neurotransmitter release
smooth muscle contraction
phosphoinositide pathway
calcium signaling
hormone secretion
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9q21
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
~42 kDa (alpha subunit)
|
|
gptkbp:mutationAssociatedWith
|
oncogenic activation
|
|
gptkbp:OMIM
|
600998
|
|
gptkbp:regulates
|
intracellular calcium levels
|
|
gptkbp:relatedTo
|
G11 protein
G14 protein
G15 protein
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
heterotrimer
|
|
gptkbp:subclassOf
|
heterotrimeric G protein
|
|
gptkbp:UniProtID
|
P50148
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:bfsLayer
|
5
|