|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Krox-24
gptkb:NGFI-A
gptkb:TIS8
gptkb:Zif268
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
gptkb:synaptic_plasticity
inflammation
memory formation
|
|
gptkbp:discoveredBy
|
J. Milbrandt
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:DNA_binding_domain
|
zinc finger
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000120738
1958
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
heart
liver
immune cells
|
|
gptkbp:expression_induced_by
|
gptkb:trauma
stress
growth factors
neuronal activity
|
|
gptkbp:fullName
|
gptkb:Early_growth_response_protein_1
|
|
gptkbp:function
|
transcription factor
response to stimuli
regulation of cell growth
regulation of differentiation
|
|
gptkbp:GO_term
|
gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated)
GO:0003700 (DNA-binding transcription factor activity)
|
|
gptkbp:HGNC_ID
|
3238
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Egr1
|
|
gptkbp:locatedOnChromosome
|
gptkb:human_chromosome_5
mouse chromosome 18
|
|
gptkbp:molecularWeight
|
~59 kDa
|
|
gptkbp:OMIM
|
128990
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
EGR1 (human)
egr-1 (rat)
|
|
gptkbp:proteinFamily
|
gptkb:EGR_family
|
|
gptkbp:regulates
|
gptkb:Fos
gptkb:PTEN
gptkb:p53
gptkb:TGF-beta
apoptosis
cell proliferation
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:P18146
|
|
gptkbp:bfsParent
|
gptkb:Zif268
gptkb:Early_Growth_Response_Protein_1
|
|
gptkbp:bfsLayer
|
7
|