Zif268

GPTKB entity

Statements (48)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:EGR1
gptkb:Krox-24
gptkb:NGFI-A
gptkb:ZENK
gptkbp:contains zinc finger domains
gptkbp:encodes gptkb:EGR1_protein
gptkbp:Entrez_Gene_ID 1958
gptkbp:expressedIn gptkb:cortex
brain
hippocampus
gptkbp:firstDescribed 1987
gptkbp:function transcription factor
regulation of gene expression
gptkbp:hasRole gptkb:cancer
gptkb:long-term_potentiation
addiction
development
wound healing
immune response
stress response
psychiatric disorders
endocrine regulation
cardiovascular function
immediate early gene response
response to environmental stimuli
gptkbp:HGNC_ID 3238
https://www.w3.org/2000/01/rdf-schema#label Zif268
gptkbp:inducedBy growth factors
seizures
neuronal stimulation
gptkbp:involvedIn learning
neuronal plasticity
memory formation
gptkbp:locatedOnChromosome gptkb:human_chromosome_5q31.2
gptkbp:OMIM 128990
gptkbp:orthologInMouse gptkb:Egr1
gptkbp:proteinFamily gptkb:EGR_family
gptkbp:regulates gptkb:synaptic_plasticity
apoptosis
differentiation
cell growth
target genes in the brain
gptkbp:response neuronal activity
gptkbp:species gptkb:Homo_sapiens
gptkbp:UniProtID gptkb:P18146
gptkbp:bfsParent gptkb:EGR1
gptkbp:bfsLayer 6