Early growth response protein 1

URI: https://gptkb.org/entity/Early_growth_response_protein_1
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Krox-24
gptkb:NGFI-A
gptkb:Zif268
EGR-1
gptkbp:associatedWith gptkb:cancer
inflammation
neural plasticity
gptkbp:biologicalProcess apoptosis
cell differentiation
cell growth
DNA binding
response to growth factors
gptkbp:domain zinc finger domain
gptkbp:encodedBy gptkb:EGR1_gene
gptkbp:Entrez_Gene_ID 1958
gptkbp:firstDescribed 1987
gptkbp:function transcription factor
gptkbp:HGNC_ID 3238
https://www.w3.org/2000/01/rdf-schema#label Early growth response protein 1
gptkbp:length 543 amino acids
gptkbp:locatedOnChromosome 5q31.2
gptkbp:molecularWeight 57 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:phosphorylates Serine 26
Serine 30
Serine 350
gptkbp:proteinFamily gptkb:EGR_family
gptkbp:regulates gptkb:synaptic_plasticity
cell proliferation
wound healing
cellular senescence
angiogenesis
immune response
neuronal activity
learning and memory
inflammatory response
fibrosis
p53 pathway
adipogenesis
TGF-beta signaling
osteogenesis
vascular remodeling
expression of target genes
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID gptkb:P18146
gptkbp:bfsParent gptkb:EGR1_protein
gptkbp:bfsLayer 7