Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
RACGAP1
|
| gptkbp:cellularComponent |
gptkb:nucleus
gptkb:cytoplasm midbody |
| gptkbp:discoveredBy |
1999
|
| gptkbp:encodedBy |
RACGAP1 gene
|
| gptkbp:Entrez_Gene_ID |
29127
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
GTPase-activating protein for Rac and Cdc42
|
| https://www.w3.org/2000/01/rdf-schema#label |
MgcRacGAP
|
| gptkbp:interactsWith |
gptkb:Ect2
gptkb:PRC1 Aurora B kinase |
| gptkbp:involvedIn |
cell cycle regulation
cytokinesis |
| gptkbp:locale |
midbody during cytokinesis
|
| gptkbp:locatedOnChromosome |
12q13.12
|
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:phosphorylates |
Aurora B kinase
|
| gptkbp:regulates |
gptkb:RhoA
gptkb:Rac1 gptkb:Cdc42 gptkb:Rho_GTPases |
| gptkbp:requires |
cytokinesis
|
| gptkbp:structure |
contains RhoGAP domain
contains nuclear localization signal contains coiled-coil domain |
| gptkbp:UniProtID |
Q9H0H5
|
| gptkbp:bfsParent |
gptkb:Ect2
|
| gptkbp:bfsLayer |
7
|