Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:biological_pathway
|
| gptkbp:alsoKnownAs |
Epidermal Growth Factor signaling pathway
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
tumorigenesis |
| gptkbp:foundIn |
animals
|
| gptkbp:involves |
gptkb:EGF
gptkb:EGFR gptkb:PLCĪ³ gptkb:PI3K gptkb:RAS gptkb:RAF gptkb:SOS gptkb:AKT gptkb:ERK gptkb:GRB2 gptkb:MEK |
| gptkbp:KEGGID |
hsa04012
|
| gptkbp:launched |
binding of EGF to EGFR
|
| gptkbp:Reactome |
gptkb:R-HSA-177929
|
| gptkbp:result |
cell differentiation
cell proliferation cell survival cell migration |
| gptkbp:studiedIn |
cancer research
cell biology |
| gptkbp:target |
monoclonal antibodies
tyrosine kinase inhibitors |
| gptkbp:bfsParent |
gptkb:MAPK3
gptkb:p44_MAPK gptkb:Sprouty4 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
EGF signaling pathway
|