EGF signaling pathway

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf biological pathway
gptkbp:alsoKnownAs Epidermal Growth Factor signaling pathway
gptkbp:dysregulationAssociatedWith gptkb:cancer
tumorigenesis
gptkbp:foundIn animals
https://www.w3.org/2000/01/rdf-schema#label EGF signaling pathway
gptkbp:involves gptkb:EGF
gptkb:EGFR
gptkb:PLCγ
gptkb:PI3K
gptkb:RAS
gptkb:RAF
gptkb:SOS
gptkb:AKT
gptkb:ERK
gptkb:GRB2
gptkb:MEK
gptkbp:KEGGID hsa04012
gptkbp:launched binding of EGF to EGFR
gptkbp:Reactome gptkb:R-HSA-177929
gptkbp:result cell differentiation
cell proliferation
cell survival
cell migration
gptkbp:studiedIn cancer research
cell biology
gptkbp:target monoclonal antibodies
tyrosine kinase inhibitors
gptkbp:bfsParent gptkb:MAPK3
gptkb:p44_MAPK
gptkb:Sprouty4
gptkbp:bfsLayer 7