|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:ATF4
CREB-2
|
|
gptkbp:binds
|
gptkb:cAMP_response_element_(CRE)
|
|
gptkbp:encodes
|
cAMP response element-binding protein 2
|
|
gptkbp:Entrez_Gene_ID
|
468
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:gene
|
gptkb:CREB2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CREB2
|
|
gptkbp:interactsWith
|
gptkb:CBP
gptkb:CREB1
gptkb:ATF3
gptkb:ATF6
|
|
gptkbp:involvedIn
|
gptkb:synaptic_plasticity
memory formation
|
|
gptkbp:locatedOnChromosome
|
22q13.1 (human)
|
|
gptkbp:memberOf
|
CREB protein family
|
|
gptkbp:OMIM
|
600003
|
|
gptkbp:phosphorylates
|
gptkb:MAPK
gptkb:protein_kinase_C
gptkb:protein_kinase_A
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
cell survival
learning
gene expression
metabolism
immune response
synaptic transmission
neuronal differentiation
memory consolidation
autophagy
amino acid metabolism
long-term memory
cellular stress response
stress response
circadian rhythm
osteoblast differentiation
gluconeogenesis
endoplasmic reticulum stress response
CREB1 activity
synaptic growth
|
|
gptkbp:UniProtID
|
P18848
|
|
gptkbp:bfsParent
|
gptkb:ATF2
gptkb:ATF1
|
|
gptkbp:bfsLayer
|
7
|