Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:PGHS-1
gptkb:Prostaglandin-endoperoxide_synthase_1 |
| gptkbp:discoveredBy |
1976
|
| gptkbp:EC_number |
1.14.99.1
|
| gptkbp:encodedBy |
PTGS1 gene
|
| gptkbp:expressedIn |
most tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
many mammals |
| gptkbp:fullName |
gptkb:Cyclooxygenase-1
|
| gptkbp:function |
catalyzes conversion of arachidonic acid to prostaglandin H2
|
| gptkbp:gene |
gptkb:PTGS1
|
| https://www.w3.org/2000/01/rdf-schema#label |
COX1
|
| gptkbp:inhibitedBy |
gptkb:NSAIDs
gptkb:aspirin |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9q32-q33.3_(human)
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
nuclear envelope |
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:notToBeConfusedWith |
MT-CO1 (mitochondrial cytochrome c oxidase subunit 1)
|
| gptkbp:OMIM |
600262
|
| gptkbp:relatedTo |
gptkb:COX2
|
| gptkbp:role |
platelet aggregation
regulation of gastric mucosa renal blood flow |
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P23219
|
| gptkbp:bfsParent |
gptkb:P00441
|
| gptkbp:bfsLayer |
6
|