aspirin

GPTKB entity

Statements (57)
Predicate Object
gptkbp:instanceOf gptkb:drug
nonsteroidal anti-inflammatory drug
gptkbp:aroma odourless or faint vinegar-like odor
gptkbp:ATCCode B01AC06
gptkbp:brand gptkb:Bayer
gptkb:Bufferin
gptkb:Ecotrin
gptkbp:CASNumber 50-78-2
gptkbp:chemicalFormula C9H8O4
gptkbp:color white
gptkbp:contraindication asthma
peptic ulcer
children with viral infections
bleeding disorders
pregnancy (third trimester)
gptkbp:discoveredBy gptkb:Felix_Hoffmann
gptkbp:discoveredIn 1897
gptkbp:eliminationHalfLife 15–30 hours (high dose)
2–3 hours (low dose)
gptkbp:excretion urine
gptkbp:firstMarketedBy gptkb:Bayer
https://www.w3.org/2000/01/rdf-schema#label aspirin
gptkbp:IUPACName 2-acetoxybenzoic acid
gptkbp:KEGGID D00109
gptkbp:legalStatus OTC (over-the-counter)
gptkbp:mechanismOfAction irreversible COX inhibitor
gptkbp:MedlinePlusID a682878
gptkbp:meltingPoint 135°C
gptkbp:MeSH_ID D001241
gptkbp:metabolism liver
gptkbp:molecularWeight 180.16 g/mol
gptkbp:origin derived from willow bark
gptkbp:pregnancyCategory D (US, third trimester)
gptkbp:PubChem_CID 2244
CHEMBL25
DB00945
gptkbp:riskFactor gptkb:Reye's_syndrome_in_children
gptkbp:routeOfAdministration oral
rectal
gptkbp:sideEffect gastrointestinal bleeding
allergic reaction
ulcer
gptkbp:solubility 3 g/L (20°C)
gptkbp:UNII R16CO5Y76E
gptkbp:usedFor pain relief
anti-inflammatory
fever reduction
prevention of heart attack
prevention of stroke
antiplatelet
gptkbp:bfsParent gptkb:Dengue_Fever
gptkb:Coronary_artery_disease
gptkb:Osler-Vaquez_disease
gptkb:IG_Farben
gptkb:warfarin
gptkb:Felix_Hoffmann
gptkbp:bfsLayer 5