|
gptkbp:instanceOf
|
gptkb:nonsteroidal_anti-inflammatory_drug
gptkb:drug
|
|
gptkbp:aroma
|
odourless or faint vinegar-like odor
|
|
gptkbp:ATCCode
|
B01AC06
|
|
gptkbp:brand
|
gptkb:Bayer
gptkb:Bufferin
gptkb:Ecotrin
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:chemicalFormula
|
C9H8O4
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
gptkb:peptic_ulcer
asthma
children with viral infections
bleeding disorders
pregnancy (third trimester)
|
|
gptkbp:discoveredBy
|
gptkb:Felix_Hoffmann
|
|
gptkbp:discoveredIn
|
1897
|
|
gptkbp:eliminationHalfLife
|
15–30 hours (high dose)
2–3 hours (low dose)
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:firstMarketedBy
|
gptkb:Bayer
|
|
gptkbp:IUPACName
|
2-acetoxybenzoic acid
|
|
gptkbp:KEGGID
|
D00109
|
|
gptkbp:legalStatus
|
OTC (over-the-counter)
|
|
gptkbp:mechanismOfAction
|
irreversible COX inhibitor
|
|
gptkbp:MedlinePlusID
|
a682878
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:MeSH_ID
|
D001241
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
180.16 g/mol
|
|
gptkbp:origin
|
derived from willow bark
|
|
gptkbp:pregnancyCategory
|
D (US, third trimester)
|
|
gptkbp:PubChem_CID
|
2244
CHEMBL25
DB00945
|
|
gptkbp:riskFactor
|
gptkb:Reye's_syndrome_in_children
|
|
gptkbp:routeOfAdministration
|
oral
rectal
|
|
gptkbp:sideEffect
|
gastrointestinal bleeding
allergic reaction
ulcer
|
|
gptkbp:solubility
|
3 g/L (20°C)
|
|
gptkbp:UNII
|
R16CO5Y76E
|
|
gptkbp:usedFor
|
pain relief
anti-inflammatory
fever reduction
prevention of heart attack
prevention of stroke
antiplatelet
|
|
gptkbp:bfsParent
|
gptkb:Coronary_artery_disease
gptkb:Osler-Vaquez_disease
|
|
gptkbp:bfsLayer
|
5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
aspirin
|