|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CDKN1A
gptkb:p21
gptkb:CIP1
gptkb:WAF1
|
|
gptkbp:alternativeName
|
gptkb:CIP1
gptkb:WAF1
gptkb:CAP20
gptkb:MDA-6
gptkb:SDI1
gptkb:CDKN1
|
|
gptkbp:associatedWith
|
cellular senescence
DNA damage response
tumor suppression
|
|
gptkbp:discoveredBy
|
Xiong et al., 1993
|
|
gptkbp:encodes
|
gptkb:p21_protein
|
|
gptkbp:Entrez_Gene_ID
|
1026
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
cell cycle arrest
inhibition of CDK2 and CDK1
regulation of G1/S and G2/M transitions
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
1784
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CDKN1A gene
|
|
gptkbp:inhibitedBy
|
gptkb:cyclin-dependent_kinases
|
|
gptkbp:involvedIn
|
apoptosis
cell differentiation
response to stress
|
|
gptkbp:length
|
164 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
gptkb:6p21.2
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:OMIM
|
116899
|
|
gptkbp:orthologInMouse
|
gptkb:Cdkn1a
|
|
gptkbp:product
|
gptkb:p21Cip1/Waf1
|
|
gptkbp:proteinFamily
|
gptkb:CDK_inhibitor_family
|
|
gptkbp:regulates
|
gptkb:p53_protein
gptkb:p53
cell cycle
|
|
gptkbp:UniProtID
|
gptkb:P38936
|
|
gptkbp:bfsParent
|
gptkb:p21
|
|
gptkbp:bfsLayer
|
6
|