Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:example |
gptkb:p15INK4b
gptkb:p16INK4a gptkb:p18INK4c gptkb:p19INK4d gptkb:p21 gptkb:p27 gptkb:p57 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
cell cycle arrest
|
| gptkbp:includes |
gptkb:INK4_family
Cip/Kip family |
| gptkbp:inhibitedBy |
gptkb:cyclin-dependent_kinases
|
| gptkbp:involves |
cellular senescence
DNA damage response |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:regulates |
growth factors
oncogenes cell cycle |
| gptkbp:role |
tumor suppression
|
| gptkbp:bfsParent |
gptkb:CDKN1A_gene
gptkb:CDK-interacting_protein/kinase_inhibitory_protein_family |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
CDK inhibitor family
|